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Well-differentiated liposarcoma

3 associated genes
4 signs/symptoms

PROTEIN INTERACTIONS: 1

Triose phosphate-isomerase deficiency

1 OMIM reference -
1 associated gene
9 signs/symptoms

Well-differentiated liposarcoma

Triose phosphate-isomerase deficiency

CDK4	(UniProt - OMIM)		TPI1	(UniProt - OMIM)
HMGA2	(UniProt - OMIM)
MDM2	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	MDM2	(0.63)	TPI1

Citations in the biomedical literature:

Well-differentiated liposarcoma		Triose phosphate-isomerase deficiency
	Synonym(s): - ALT - Atypical lipoma - Atypical lipomatous tumor - WDLS		Synonym(s): (no synonyms)

	Classification (Orphanet): - Rare oncologic disease		Classification (Orphanet): - Inborn errors of metabolism - Rare genetic disease - Rare hematologic disease - Rare neurologic disease

	Classification (ICD10): - Neoplasms -		Classification (ICD10): - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -

	Epidemiological data: Class of prevalence: unknown Average age onset: adulthood Average age of death: adult Type of inheritance: sporadic		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: neonatal/infancy Average age of death: - Type of inheritance: autosomal recessive

	External references: No OMIM references No MeSH references		External references: 1 OMIM reference - No MeSH references

Well-differentiated liposarcoma		Triose phosphate-isomerase deficiency
	Very frequent - Soft tissue sarcoma / cancer / tumor / liposarcoma / myosarcoma - Subcutaneous nodules / lipomas / tumefaction / swelling Occasional - Functional anomalies of the kidney and the urinary tract - Intestinal transit disorder		Very frequent - Autosomal recessive inheritance - Functional anomalies of the nervous system - Hypotonia - Immunodeficiency / increased susceptibility to infections / recurrent infections - Muscle hypotrophy / atrophy / dystrophy / agenesis / amyotrophy Frequent - Diaphragmatic hernia / defect / agenesis - Stillbirth / neonatal death Occasional - Cardiomyopathy / hypertrophic / dilated - Nerve conduction abnormality